Cell Biology 双语教学大纲
1. Introduction
● Unity and diversity of cells
● Cells under the microscope
● The procaryatic cell
● The eucaryotic cell
2. The Chemical Basis of Cells
● Chemical bonds
● Molecules in cells
● Macromolecules in cells
3. Research Methods of Cell Biology(反映在各章节中，或通过试验课学习)
4. Membrane Structure and Transport
● The lipid bilayer
● Membrane proteins
● Cell-Cell junctions
● Extracellular matrix
● Passive transport of substances
● Active transport of substances
5. Intracellular Compartment and Vesicular Transport
● Membrane-enclosed organelles
● Protein sorting
● Vesicular transport
● Secretory pathways
● Endocytic pathways
6. Mitochondria and Chloroplasts
● Mitochondria and oxidative phosphorylation
● Chloroplasts and photosynthesis
● The origins of chloroplasts and mitochondria
7. Cytoskeleton
● Microtubules
● Actin filaments
● Muscle contraction
● Intermediate filaments
● Membrane skeleton and nuclear skeleton
8. Cell Communication and Signaling
● General principles of cell signaling
● Nitric oxide crosses the plasma membrane and actives intracellular
● Ion-Protein-Linked receptors convert chemical signals into electrical signals
● G-Protein-Linked receptors
● Enzyme linked receptors
● Signaling by focal adhesion kinases
● Convergence divergence and signal network system
9. Nucleus and Chromosomes
● Nuclear envelope and nuclear pore complex
● Chromatin and chromosomes
● Nucleolus and ribosome biogenesis
● Nuclear matrix
10. Ribosome
● Shapes and compositions of ribosome
● The RNA message is decoded on ribosome
● The ribosome is a ribozyme
● Proteins are made on polyribosomes
11. Cell-Cycle and Cell Division
● Overview of the cell cycle
● The cell cycle control system
● Mitosis
● Meiosis
12. Cell Differentiation
● Totipotency
● House-keeping gene and tissue-specific gene
● Gene differential express
● Transcriptional level control
● Processing level control
● Translational level control
● Stem cell
● Cancer cell
13. Cell Senescence and Cell Death
● Hayflick Limitation
● Intracellular Conditions for Senescence
● Structural change of senescence cells
● Molecular basis of cell ageing
● Apoptosis
● Necrosis and apoptosis
● Morphology features of apoptic bodies
● DNA ladders
● Apoptosis is regulated by the Bcl-2 family of intracellular proteins
● Extracellular control of cell numbers and cell size
