当前位置: 首页  教学团队  丁宁 副教授
丁宁 副教授

 

丁宁    副教授


受教育及工作经历:

2013 – 今,复旦大学药学院药物化学教研室,副教授

2009 – 2012复旦大学药学院药物化学教研室,讲师

2007 – 2009,美国普度大学 (Purdue University) 化学系,博士后

2004 – 2007,中国海洋大学医药学院,药物化学专业,博士

2001 – 2004,中国海洋大学医药学院,药物化学专业,硕士

1997 – 2001,青岛海洋大学水产学院,药物化学专业,学士

研究兴趣与主要研究方向        

1. 糖缀合物的合成方法学与构效关系研究

2. 分子靶点抗肿瘤药物的设计与构效关系研究

3. 糖探针/糖芯片的制备与应用


获奖

2013年复旦大学青年教师讲课比赛(医科组)二等奖。

2013年复旦大学第一三共制药奖教金

2012年入选复旦大学优秀青年人才项目“卓学计划”(2012-2014)。

2012年复旦大学药学院青年教师讲课比赛一等奖。

2011年复旦大学药学院年度个人优秀奖。

2010年复旦大学药学院青年教师讲课比赛二等奖。



讲授课程:

《药物化学I》

《化学生物学导论》

《糖化学》

《高等药物化学》

《有机化学实验》

《高等有机化学实验》

学术任职:

担任以下学术期刊的审稿人:

Chemical Communication

Journal of Carbohydrate Chemistry

Tetrahedron Letters

Bioorganic & Medicinal Chemistry

Bioorganic & Medicinal Chemistry Letters

Chemical Biology and Drug Design

Chinese Chemical Letters

有机化学


代表性论文:


1. Yichu Liu, Xiaoyan Xu, Qi Gao, Shiqiang Yan, YingxiaLi, Ning Ding*. Rapid accessto 6”-functionalized alfa-galactosylceramides by using 2-naphthylmethyl ether as the permanent protecting group. Bioorganic & Medicinal Chemistry Letters, 2017, in press, DOI: 10.1016/j.bmcl.2017.02.055.

2. Dongming Yao#, Yichu Liu#, Shiqiang Yan, Yingxia Li, Chun Hu, Ning Ding*. Evidence of robust participation by equatorial 4-O group in glycosylation on a 2-azido-2-deoxy-glucopyranosyl donor. Chemical Communications, 2017, published online, DOI: 10.1039/C7CC00274B.

3. Xiaozhe Fu, Mingming Zhang, Qi Gao, Fengling Yang, Yingxia Li, Ning Ding*. Total synthesis of two diastereomers of megastigmane glycoside lauroside B. Journal of Carbohydrate Chemistry, 2015, 34, 445-459.

4. Kun Shao, Yu Zhang, Ning Ding, Shixian Huang, Jiqin Wu, Jianfeng Li, Chunfu Yang, Qibin Leng, Liya Ye, Jinning Lou, Liping Zhu, Chen Jiang*. Functionalized nanoscale micelles with brain targeting ability and intercellular microenvironment biosensitivity for anti‐intracranial infection applications. Advanced Healthcare Materials, 2015, 4, 291-300.

5. Kun Shao, Ning Ding, Shixian Huang, Sumei Ren, Yu Zhang, Yuyang Kuang, Yubo Guo, Haojun Ma, Sai An, Yingxia Li, Chen Jiang*. Smart nanodevice combined tumor-specific vector with cellular microenvironment-triggered property for highly effective antiglioma therapy. ACS Nano. 2014, 8, 1191-1203.

6. Yongfeng Tao, NingDing*, Sumei Ren, Yingxia Li*. Heck-type cross-coupling between halo-exo-glycals and endo-glycals: a practical way to achieve C-glycosidic disaccharides. Tetrahedron Letters 2013, 54, 6101-6104.

7. Ning Ding, Qing Chen, Wei Zhang, Sumei Ren, Ying Guo*, YingxiaLi*. Structure-activity relationships of saponin derivatives: A series ofentry inhibitors for highly pathogenic H5N1 influenza virus. European Journal of Medicinal Chemistry 2012, 53, 316-326.

8. Ning Ding, Zaihong Zhang, Wei Zhang, Yuexing Chun, Peng Wang, Huimin Qi, Shan Wang, Yingxia Li*. Synthesis and antibacterial evaluation of a series of acetylated oligorhamnoside derivatives. Carbohydrate Research 2011, 346, 2126-2135.

9. Ning Ding, Xiaoguang Du, Wei Zhang, Zhichao Lu, Yingxia Li*. Synthesis andbiological evaluation of cytotoxic activity of naphtho[2,1-]pyrrolo[3,4-c]carbazole-5,7(6H, 12H)-dione glycosides. Bioorganic & Medicinal Chemistry Letters2011, 21, 3531-3535.

10. Ning Ding, Wei Zhang, Guolai Lv, Yingxia Li*. Synthesis and biological evaluation of antifungal activities of novel 1,2-trans glycosphingolipids. Archiv der Pharmazie 2011, 344, 786-793.